BDBM50582397 CHEMBL5072089

SMILES CC(C)c1n[nH]c2nccc(-n3cnc(c3)-c3cccnc3)c12

InChI Key InChIKey=YSZFOKSPOWYUHM-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50582397   

TargetHeat shock protein HSP 90-alpha(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50582397(CHEMBL5072089)
Affinity DataIC50: 2.93E+5nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-alpha incubated for 2 hrs followed by FITC-GDA addition and measured after 5 hrs by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50582397(CHEMBL5072089)
Affinity DataIC50: 8.90E+4nMAssay Description:Binding affinity to human HSP90-beta by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetEndoplasmin(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50582397(CHEMBL5072089)
Affinity DataIC50: 3.00E+5nMAssay Description:Binding affinity to GRP94 (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHeat shock protein 75 kDa, mitochondrial(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50582397(CHEMBL5072089)
Affinity DataIC50: 3.00E+5nMAssay Description:Binding affinity to TRAP1 (unknown origin) by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Taiho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50582397(CHEMBL5072089)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to human HSP90-alpha N-terminal domain assessed as change in enthalpy by measuring dissociation constant at 100 uM at 25 degC by iso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed