BDBM50582931 CHEMBL5083596

SMILES COc1ccc(cc1)C(=O)CSc1nc(Nc2ccc(cc2)S(N)(=O)=O)c(C#N)c(n1)C(C)C

InChI Key InChIKey=JNXXZYRIJMSMRT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50582931   

TargetCarbonic anhydrase 12(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582931(CHEMBL5083596)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human CA12 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582931(CHEMBL5083596)
Affinity DataKi:  82nMAssay Description:Inhibition of human CA2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582931(CHEMBL5083596)
Affinity DataKi:  92nMAssay Description:Inhibition of human CA9 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50582931(CHEMBL5083596)
Affinity DataKi:  766nMAssay Description:Inhibition of human CA1 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed