BDBM50583157 CHEMBL5082230

SMILES Fc1cnc(Nc2ccc(cn2)N2CCNCC2)nc1-c1ccc2nccnc2c1

InChI Key InChIKey=IRQBQPNOWKSJBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50583157   

TargetCyclin-dependent kinase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583157(CHEMBL5082230)
Affinity DataIC50: 118nMAssay Description:Inhibition of CDK6 (unknown origin) by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50583157(CHEMBL5082230)
Affinity DataIC50: 318nMAssay Description:Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA peptide substrate incubated for 2 hrs by by electrophoretic mobility change analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed