BDBM50583430 CHEMBL5076178

SMILES COc1ccc(Nc2ncc(C)c(n2)N2CCC3(CCNC3=O)CC2)cc1OC

InChI Key InChIKey=KTRYMHRWJYJLMG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50583430   

TargetTyrosine-protein kinase JAK1(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583430(CHEMBL5076178)
Affinity DataIC50: 273nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583430(CHEMBL5076178)
Affinity DataIC50: 360nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583430(CHEMBL5076178)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583430(CHEMBL5076178)
Affinity DataIC50: 90nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed