BDBM50583561 CHEMBL5078388

SMILES [H][C@]12Cc3ccc(OC(F)(F)F)cc3[C@@]3(CCCC[C@]13[H])CCN2C

InChI Key

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50583561   

TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataIC50: 31nMAssay Description:Inhibition of human SERT receptor expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NET expressed in human HEK293 cells assessed as inhibition of substrate transport measured after 1 hr by flourescence based plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-Citalopram from SERT receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  757nMAssay Description:Displacement of [3H]-Citalopram from sigma-1 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi:  833nMAssay Description:Displacement of [3H]-Citalopram from sigma-2 receptor (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
The University of Kansas

Curated by ChEMBL
LigandPNGBDBM50583561(CHEMBL5078388)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Citalopram from NET (unknown origin) expressed in HEK cell membrane incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed