BDBM50583626 CHEMBL5077503

SMILES CC[C@H](Cc1ccc(cc1)C(=O)NCc2ccc(cc2C(F)(F)F)OC)C(=O)O

InChI Key InChIKey=VPAHYLNIDWFBPW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50583626   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50583626(CHEMBL5077503)
Affinity DataEC50:  270nMAssay Description:Agonist activity at recombinant N-terminal His6 -tagged GFP fused PPARgamma LBD (unknown origin) (203 to 477 residues) expressed in Escherichia cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional epoxide hydrolase 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50583626(CHEMBL5077503)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human C-terminal sEH (222 to 555 residues) expressed in Escherichia coli BL21-DE3 using PHOME as substrate assessed as redu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50583626(CHEMBL5077503)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human GAL4 DBD-fused PPARgamma LBD (203 to 505 residues) transfected in HEK293T cells assessed as fold activation incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)