BDBM50583649 CHEMBL5094345

SMILES COc1cc(CN(c2cc(cnc2OC)-c2cc(OC3CCOCC3)c3ncnc(C)c3c2)S(=O)(=O)c2ccc(F)cc2F)c(cc1OC)[N+]([O-])=O

InChI Key InChIKey=MZNFIPXMASIVMQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50583649   

LigandPNGBDBM50583649(CHEMBL5094345)
Affinity DataIC50: 343nMAssay Description:Inhibition of PI3K alpha (unknown origin) using PIP2 as substrate incubated in dark at room temperature for 1 hr in presence of ATP by ADP-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50583649(CHEMBL5094345)
Affinity DataIC50: 838nMAssay Description:Inhibition of PI3K beta (unknown origin) using PIP2 as substrate incubated in dark at room temperature for 1 hr in presence of ATP by ADP-Glo lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50583649(CHEMBL5094345)
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of PI3K gamma (unknown origin) using PIP2 as substrate incubated in dark at room temperature for 1 hr in presence of ATP by ADP-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50583649(CHEMBL5094345)
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of PI3K delta (unknown origin) using PIP2 as substrate incubated in dark at room temperature for 1 hr in presence of ATP by ADP-Glo lumine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
LigandPNGBDBM50583649(CHEMBL5094345)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of PI3K alpha (unknown origin) using PIP2 as substrate irradiated with 365 nm of UV exposure for 2 mins and incubation in dark at room tem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed