BDBM50583791 CHEMBL5091473

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC1=O)C(N)=O

InChI Key InChIKey=NVEUMOAVDZBVON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50583791   

TargetCoagulation factor XII(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583791(CHEMBL5091473)
Affinity DataIC50: 234nMAssay Description:Inhibition of human factor 12a using H-D-Pro-Phe-Arg-p-nitroanilide as chromogenic substrate assessed as liberation of p-nitroaniline measured every ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583791(CHEMBL5091473)
Affinity DataIC50: 311nMAssay Description:Inhibition of human factor 12a using H-D-Pro-Phe-Arg-p-nitroanilide as chromogenic substrate assessed as liberation of p-nitroaniline in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50583791(CHEMBL5091473)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human factor 10a using methoxycarbonyl-D-Nle-Gly-Arg-pNA as substrate measured after 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed