BDBM50583882 CHEMBL5085869

SMILES Cc1ccc2CC(O)Cc3nnc([C@H]4CC[C@@H](CC4)Oc4ccccn4)n3-c2c1

InChI Key InChIKey=DDCXBLIOHUHHNV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50583882   

TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50583882(CHEMBL5085869)
Affinity DataIC50: 390nMAssay Description:Inhibition of human V1A receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescent plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50583882(CHEMBL5085869)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-arginine-vasopressin from human V1A receptor expressed in human 1321N1 cell membranes incubated for 60 mins by radioligand bindi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed