BDBM50584076 CHEMBL5083059

SMILES Cc1ccc(s1)C(\Nc1cccc(Br)c1)=N\O

InChI Key InChIKey=IXDWQKVBIPDMHS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584076   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50584076(CHEMBL5083059)
Affinity DataEC50:  54nMAssay Description:Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50584076(CHEMBL5083059)
Affinity DataIC50: 74nMAssay Description:Inhibition of human IDO1 protein assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate by methylene blue reagent base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50584076(CHEMBL5083059)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of recombinant human TDO2 protein assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed