BDBM50584947 CHEMBL5074478

SMILES CC1=C(C#N)c2nc(N)c(C#N)c(C)c2\C1=C/c1ccc(o1)-c1cc(ccc1Cl)C(O)=O

InChI Key InChIKey=CKEZGFZETZHCNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50584947   

TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibitory activity against ATAD2 (unknown origin) at bromodomain incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Shenzhen University

Curated by ChEMBL
LigandPNGBDBM50584947(CHEMBL5074478)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 180 min by Tr-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed