BDBM50584961 CHEMBL5076697

SMILES FC(F)(F)c1cnc(Nc2ccc(nc2)C(=O)NC2CC2)nc1NCC1CCNCC1

InChI Key InChIKey=RDCSFKPLLCCMQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584961   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584961(CHEMBL5076697)
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal GST tagged human recombinant wild type FLT-3 (564-993 residues) expressed in baculovirus infected Sf21 insect cells using TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584961(CHEMBL5076697)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal GST tagged human recombinant FLT3 D835Y mutant (564 residue) expressed in baculovirus infected Sf21 insect cells using TK pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584961(CHEMBL5076697)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST tagged human recombinant cKit (544 residue) expressed in baculovirus infected Sf21 insect cells using TK peptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed