BDBM50584969 CHEMBL5091395

SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(N)=O)ncc1C(F)(F)F

InChI Key InChIKey=ASLOBMSYWWVZKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50584969   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584969(CHEMBL5091395)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST tagged human recombinant wild type FLT-3 (564-993 residues) expressed in baculovirus infected Sf21 insect cells using TK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584969(CHEMBL5091395)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of N-terminal GST tagged human recombinant FLT3 D835Y mutant (564 residue) expressed in baculovirus infected Sf21 insect cells using TK pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50584969(CHEMBL5091395)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of N-terminal GST tagged human recombinant cKit (544 residue) expressed in baculovirus infected Sf21 insect cells using TK peptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed