BDBM50585145 CHEMBL5078616

SMILES COC(=O)[C@H](Cc1ccc(F)cc1)NC(=O)\C=C\c1ccc(Cl)cc1

InChI Key InChIKey=VGVNIJCMFFTFGQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585145   

TargetNitric oxide synthase, inducible(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585145(CHEMBL5078616)
Affinity DataIC50: 945nMAssay Description:Inhibition of human iNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585145(CHEMBL5078616)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of human nNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50585145(CHEMBL5078616)
Affinity DataIC50: 1.89E+5nMAssay Description:Inhibition of human eNOS assessed as reduction in L-[3H]-citrulline level using L-[3H]-arginine as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed