BDBM50585309 CHEMBL5085816

SMILES COc1cc(N(C)CCN(C)CC(C)=C)c(NC(=O)C=C)cc1Nc1nccc(Nc2cn(C)c3ccccc23)n1

InChI Key InChIKey=GGLPOFNLJZZVAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585309   

TargetEpidermal growth factor receptor(Human)
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50585309(CHEMBL5085816)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of EGFR T790M/C797S double mutant (unknown origin) using flurogenic substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50585309(CHEMBL5085816)
Affinity DataIC50: 64nMAssay Description:Inhibition of EGFR del19 (unknown origin) using flurogenic substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50585309(CHEMBL5085816)
Affinity DataIC50: 181nMAssay Description:Inhibition of wild type EGFR (unknown origin) using flurogenic substrate in presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed