BDBM50585453 CHEMBL5085109

SMILES Brc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(cc3)C(=O)CCC3CCN(Cc4ccccc4)CC3)c2c1

InChI Key InChIKey=YBNPWOYOYCFQFX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585453   

TargetAcetylcholinesterase(Mouse)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585453(CHEMBL5085109)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCholinesterase(Mouse)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585453(CHEMBL5085109)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of BuChE in mouse serum using butyrylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585453(CHEMBL5085109)
Affinity DataEC50:  169nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed