BDBM50585469 CHEMBL5092918

SMILES Fc1cccc(CN2CCC(CCC(=O)c3ccc(cc3)N3CCN(CCCCc4c[nH]c5ccc(cc45)C#N)CC3)CC2)c1

InChI Key InChIKey=OYZOYMPAEFAHEV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50585469   

TargetAcetylcholinesterase(Mouse)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585469(CHEMBL5092918)
Affinity DataIC50: 11nMAssay Description:Inhibition of AChE in mouse cortical homogenate using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCholinesterase(Mouse)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585469(CHEMBL5092918)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of BuChE in mouse serum using butyrylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50585469(CHEMBL5092918)
Affinity DataEC50:  107nMAssay Description:Agonist activity at human 5-HT1A receptor expressed in HEK293 cells incubated for 60 mins by Eu-cAMP tracer based LANCE ultra cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed