BDBM50585545 CHEMBL5074018

SMILES NC(=O)C1CCCN1C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1

InChI Key InChIKey=XDXZHIQVJAQRGY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585545   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Guizhou Medical University

Curated by ChEMBL

LigandBDBM50585545(CHEMBL5074018)Copy SMILESCopy InChI

Affinity DataIC50: 0.600nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate in presence of ATP incubated for 60 mins by ADP-glo based luminescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/7/2023
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
Guizhou Medical University

Curated by ChEMBL

LigandBDBM50585545(CHEMBL5074018)Copy SMILESCopy InChI

Affinity DataIC50: 1.40nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in presence of ATP incubated for 45 mins by Lance ultra assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/7/2023
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL