BDBM50585790 CHEMBL5076569

SMILES NCCCCN(C[C@H]1Cc2cccnc2CN1)[C@H]1CCCc2cccnc12

InChI Key InChIKey=SASWWPISKHTFAO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50585790   

TargetCytochrome P450 2D6(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human CYP2D6 using AMMC as substrate preincubated for 30 mins followed by substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of alpha 2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of alpha 2C adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of M2 mAChR receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50585790(CHEMBL5076569)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human ERG by [3H]]Astemizole binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed