BDBM50586023 CHEMBL5079287

SMILES OCCN1CCN(CC1)C(=O)C[C@H](NC(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=CFGGTYDLTXKOFX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586023   

TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586023(CHEMBL5079287)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of plasma kallikrein (unknown origin) assessed as chromogenic substrate hydrolysis using CS-31(02) as substrate incubated for 1 hr by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586023(CHEMBL5079287)
Affinity DataIC50: 12nMAssay Description:Inhibition of coagulation factor XIa (unknown origin) assessed as chromogenic substrate hydrolysis using CS-21(66) as substrate incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed