BDBM50586025 CHEMBL5079000

SMILES OC(=O)c1ccc(NC(=O)[C@H](CC(=O)N2CCCN(CC3CC3)CC2)NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=HOAXXKWHNWIOBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586025   

TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586025(CHEMBL5079000)
Affinity DataIC50: 67nMAssay Description:Inhibition of coagulation factor XIa (unknown origin) assessed as chromogenic substrate hydrolysis using CS-21(66) as substrate incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586025(CHEMBL5079000)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of plasma kallikrein (unknown origin) assessed as chromogenic substrate hydrolysis using CS-31(02) as substrate incubated for 1 hr by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed