BDBM50586027 CHEMBL5090877

SMILES OC(=O)c1ccc(NC(=O)[C@H](CC(=O)N2CCN(CC2)c2ccccc2)NC(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)cc1

InChI Key InChIKey=AVSRJYMYJIKOOD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50586027   

TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 2.79E+4nMAssay Description:Inhibition of plasma kallikrein (unknown origin) assessed as chromogenic substrate hydrolysis using CS-31(02) as substrate incubated for 1 hr by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 3.40E+5nMAssay Description:Inhibition of coagulation factor Xa (unknown origin) assessed as chromogenic substrate using CS-11(22) as substrate incubated for 1 hr by spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProthrombin(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 4.60E+5nMAssay Description:Inhibition of thrombin (unknown origin) assessed as chromogenic substrate using CS-10(38) as substrate incubated for 1 hr by spectrophotometer based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 14nMAssay Description:Inhibition of coagulation factor XIa (unknown origin) assessed as chromogenic substrate hydrolysis using CS-21(66) as substrate incubated for 1 hr by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of FXIa (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50586027(CHEMBL5090877)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PKal (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed