BDBM50586459 CHEMBL5080510

SMILES COc1cc2ncnc(NCCc3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=AJMTUUMTBJOKEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586459   

TargetAurora kinase A(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50586459(CHEMBL5080510)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal GST tagged Aurora A (unknown origin) expressed in recombinant baculovirus-infected Sf9 cells using tetra(LRRWSLG) as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAurora kinase A(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50586459(CHEMBL5080510)
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-tagged AURA Ser123 to 401 residues) (unknown origin) expressed in Sf9 insect cells using tetra-LLRASLG peptide as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed