BDBM50586957 CHEMBL5077363

SMILES FC(F)(F)c1cc(CS(=O)(=O)C2CC2)ccc1CNC(=O)c1ccc2[nH]ccc2c1

InChI Key InChIKey=NHUBZKOKSPABBB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50586957   

TargetBifunctional epoxide hydrolase 2(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50586957(CHEMBL5077363)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human full length sEH assessed as reduction in 6-methoxy-2-naphthaldehyde formation using PHOME as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University

Curated by ChEMBL
LigandPNGBDBM50586957(CHEMBL5077363)
Affinity DataEC50:  1.48E+3nMAssay Description:Partial agonist activity at GAL4-tagged human PPARgamma LBD expressed in HEK293T cells incubated for 12 to 14 hrs by dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed