BDBM50587109 CHEMBL5079787

SMILES Fc1ccccc1CNC(=O)[C@@H]1CCCCOc2cccc(CCC(=O)N[C@@H](CC(=O)N3CCC[C@@H]3C3CC3)C(=O)N1)c2

InChI Key InChIKey=QVGIFHDCHFYUMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587109   

TargetProteasome subunit beta type-5(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50587109(CHEMBL5079787)
Affinity DataIC50: 73nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5c subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50587109(CHEMBL5079787)
Affinity DataIC50: 69nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetProteasome subunit beta type-10(Human)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50587109(CHEMBL5079787)
Affinity DataIC50: 4.45E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta-2i subunit using Z-VLR-AMC as substrate measured over 1.5 to 2 hrs by plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed