BDBM50587281 CHEMBL5082029

SMILES CC(C)Oc1cc(NC(=O)N2CCCc3ccc(nc23)C(=O)C(F)(F)F)ncc1C#N

InChI Key InChIKey=DNEPJJIFRIXPKZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587281   

TargetFibroblast growth factor receptor 4(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50587281(CHEMBL5082029)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human FGFR4 expressed in baculovirus expression system using Tyr04 peptide as substrate preincubated in assay bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50587281(CHEMBL5082029)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50587281(CHEMBL5082029)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR2 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50587281(CHEMBL5082029)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1 (unknown origin) using Tyr04 peptide as substrate incubated for 1 hr in presence of ATP by FRET based Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed