BDBM50587447 CHEMBL5090553

SMILES COC(=O)\C=C1/S\C(=N/N=C/c2ccc(OCC(F)(F)F)cc2)N(C1=O)c1ccccc1

InChI Key InChIKey=LZUXHSNNOGRDOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50587447   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587447(CHEMBL5090553)
Affinity DataIC50: 7.75E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587447(CHEMBL5090553)
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by EL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Huazhong Agricultural University

Curated by ChEMBL
LigandPNGBDBM50587447(CHEMBL5090553)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate preincubated for 10 mins followed by substrate addition and measured after 1 hr by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed