BDBM50587597 CHEMBL5079033::US11661419, Example 39::US20230280220, Example 39
SMILES [H][C@@]12C[C@]1(C)Cc1[nH]nc(c1C2)-c1nc2cc(cc(O)c2[nH]1)N(C)C(=O)[C@H](C)N1CCOCC1
InChI Key InChIKey=JQIBOKWDFMIEJM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50587597
Affinity DataIC50: 8nMAssay Description:1.0M HEPES Buffer pH 7.5 solution was prepared as follows: 238.3 g HEPES free acid (Sigma) and 800 mL of water were combined, and the mixture was sti...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:ITK activity was determined by measuring the effect of a test compound in an ITK enzyme assay. 1.0 M HEPES Buffer pH 7.5 solution was prepared as fol...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of ITK (unknown origin) using BTK peptide as substrate preincubated for 30 mins followed by addition of substrate and measured after 60 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...More data for this Ligand-Target Pair