BDBM50587718 CHEMBL5185889

SMILES ONC(=O)c1ccc(Cn2sc3ccccc3c2=O)cc1

InChI Key InChIKey=ZBKIYZUDBOQUME-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50587718   

TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using RHKAcKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using acetyl-Lys(trifluoroacetyl)-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using acetyl-Lys(trifluoroacetyl)-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using acetyl-Lys(trifluoroacetyl)-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using acetyl-Lys(trifluoroacetyl)-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed