BDBM50587789 CHEMBL5188203

SMILES CCOC(=O)c1oc2ccccc2c1CBr

InChI Key InChIKey=AHTASHQCOAXTTF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587789   

TargetSerine/threonine-protein kinase PLK1(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50587789(CHEMBL5188203)
Affinity DataKd:  1.28E+4nMAssay Description:Binding affinity to human PLK1-PBD (326 to 603 residues) expressed in Escherichia coli BL21(DE3) rosetta cells by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50587789(CHEMBL5188203)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of human PLK1-PBD (326 to 603 residues) expressed in Escherichia coli BL21(DE3) rosetta cells using 5-carboxyfluorescein-GPMQSpTPLNG-OH as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed