BDBM50588433 CHEMBL5170628

SMILES Cc1c(C)c(nnc1N1CCC(CC1)NC(=O)Nc1ccc(Nc2nc(NC3CCOCC3)ncc2Cl)cc1)-c1ccnn1C

InChI Key InChIKey=IKPIGLQHWUMAAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50588433   

TargetSmoothened homolog(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588433(CHEMBL5170628)
Affinity DataIC50: 64nMAssay Description:Inhibition of SMO in mouse 3T3/HH FlashII-7 cells incubated for 36 hrs in presence of SHH by Gli-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed