BDBM50588536 CHEMBL5172295

SMILES Fc1ccc(Oc2cc3nc(NC(=O)C4CC(=O)C4)sc3cc2F)cc1NC(=O)Cc1cccc(OC(F)(F)F)c1

InChI Key InChIKey=HHEYLJSYWNFAEK-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588536   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588536(CHEMBL5172295)
Affinity DataKd:  8.60nMAssay Description:Binding affinity to recombinant human wild type partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system by KINOMEscan TM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588536(CHEMBL5172295)
Affinity DataKd: >5.00E+3nMAssay Description:Binding affinity to recombinant human wild type partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system by KINOMEscan TM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed