BDBM50588661 CHEMBL5205035

SMILES CC(C)N1CCc2cc(ccc2C1=O)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F

InChI Key InChIKey=UBHPJEJMHASIRC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50588661   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588661(CHEMBL5205035)
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK6/cyclin-D1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588661(CHEMBL5205035)
Affinity DataIC50: 495nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588661(CHEMBL5205035)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK4/cyclin-D3 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50588661(CHEMBL5205035)
Affinity DataIC50: 8.72E+3nMAssay Description:Inhibition of CDK7/cyclin H/MAT1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588661(CHEMBL5205035)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed