BDBM50588662 CHEMBL5194451

SMILES CCN1CCN(CC1)C(=O)c1ccc(Nc2ncc(F)c(n2)-c2ccc3C(=O)NCCc3c2)nc1

InChI Key InChIKey=PZNJKWXGJKXLOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50588662   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588662(CHEMBL5194451)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK6/cyclin-D1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588662(CHEMBL5194451)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK4/cyclin-D3 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed