BDBM50588663 CHEMBL5185518

SMILES Fc1cnc(Nc2ccc(cn2)N2CCNCC2)nc1-c1ccc2C(=O)NCCc2c1

InChI Key InChIKey=RONAHISFEVHOEE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50588663   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588663(CHEMBL5185518)
Affinity DataIC50: 36nMAssay Description:Inhibition of CDK6/cyclin-D1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588663(CHEMBL5185518)
Affinity DataIC50: 175nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588663(CHEMBL5185518)
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK4/cyclin-D3 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50588663(CHEMBL5185518)
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of CDK7/cyclin H/MAT1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588663(CHEMBL5185518)
Affinity DataIC50: 382nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin) in presence of ATP by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed