BDBM50588694 CHEMBL5191797

SMILES CNC(=O)c1ccc(cc1C(F)(F)F)-c1ccc(=O)n(CCc2ccc3ncc(cc3c2)-c2cnn(c2)C2CCOCC2)n1

InChI Key InChIKey=VVGBSNRZVJGQFL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50588694   

TargetHepatocyte growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588694(CHEMBL5191797)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of N-terminal His/SUMO tagged wild type human c-Met (1038 to 1346 residues) transfected in Escherichia coli using Tyr06 peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588694(CHEMBL5191797)
Affinity DataIC50: 10nMAssay Description:Inhibition of TRKC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588694(CHEMBL5191797)
Affinity DataIC50: 13nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588694(CHEMBL5191797)
Affinity DataIC50: 20nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50588694(CHEMBL5191797)
Affinity DataIC50: 164nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed