BDBM50589474 CHEMBL5191898

SMILES CN(N1CCC[C@H](C1)C(=O)NCC#N)c1ncnc2[nH]ccc12

InChI Key InChIKey=ZSDNEXABROUHAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50589474   

TargetTyrosine-protein kinase JAK1(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50589474(CHEMBL5191898)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50589474(CHEMBL5191898)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50589474(CHEMBL5191898)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed