BDBM50589624 CHEMBL5193942

SMILES Fc1cc(ccc1CNC(=O)c1ccccc1)-c1ncnc2[nH]cc(C3=CCN(CC3)C(=O)C=C)c12

InChI Key InChIKey=MLZFQUIEECNEMP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50589624   

TargetTyrosine-protein kinase BTK(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50589624(CHEMBL5193942)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of BTK (unknown origin) measured by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50589624(CHEMBL5193942)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of BTK in human TMD8 cells assessed as inhibition of BTK autophosphorylation at Tyr223 measured by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50589624(CHEMBL5193942)
Affinity DataIC50: 4.38E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed