BDBM50589675 CHEMBL5176270

SMILES Cc1nc(NC(=O)NC(=O)CC2CCCCC2)ccc1Oc1ccnc(c1)-c1cnn(C)c1

InChI Key InChIKey=XPBJIFLFRWUBPO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50589675   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Deciphera Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50589675(CHEMBL5176270)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of VEGFR2 (unknown origin) measured by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed