BDBM50589723 CHEMBL5180734::US11760752, Compound 49

SMILES Cc1cc(Oc2ccc(Cn3nc4cc(Cl)ccc4c3C(O)=O)cc2)cc(C)c1Cl

InChI Key InChIKey=UOKSFLGDGPESGV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50589723   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50589723(CHEMBL5180734 | US11760752, Compound 49)
Affinity DataKi:  1.76E+3nMAssay Description:The fluorescence polarization assays were performed in 96 well polypropylene F-bottom black microplates (Greiner Bio-One) with a final volume of 100 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
Go to US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland, Baltimore

US Patent
LigandPNGBDBM50589723(CHEMBL5180734 | US11760752, Compound 49)
Affinity DataKi:  1.76E+3nMAssay Description:Inhibition of MCL-1 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed