BDBM50590271 CHEMBL5198711

SMILES Cc1cc(C)c2nc(CSc3ncccn3)[nH]c(=O)c2c1

InChI Key InChIKey=JNLILESBBKKTIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590271   

TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590271(CHEMBL5198711)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590271(CHEMBL5198711)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed