BDBM50590369 CHEMBL5188231

SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(CC(=O)Nc3ccc(NC(=O)C4CC4)nc3)cc2)CC1

InChI Key InChIKey=RBWVZGKOJYNSAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590369   

TargetTyrosine-protein kinase ABL1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50590369(CHEMBL5188231)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of His-tagged wild type ABL (229 to 500 residues) (unknown origin) expressed in baculovirus expression system using abltide as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50590369(CHEMBL5188231)
Affinity DataIC50: 28nMAssay Description:Inhibition of His-tagged ABL-V299L mutant (unknown origin) expressed in baculovirus expression system using abltide as substrate in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed