BDBM50590736 CHEMBL5192259

SMILES [O-][N+](=O)c1ccccc1CNc1cc(cc2[nH]ncc12)C(F)(F)F

InChI Key InChIKey=TUYDYSIZNGYTJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590736   

TargetTryptophan 2,3-dioxygenase(Human)
Xihua University

Curated by ChEMBL
LigandPNGBDBM50590736(CHEMBL5192259)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human TDO (19 to 388 residues) expressed in Escherichia coli Transetta (DE3) using L-tryptophan as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Xihua University

Curated by ChEMBL
LigandPNGBDBM50590736(CHEMBL5192259)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human IDO1 (12 to 403 residues) expressed in Escherichia coli Transetta (DE3) using L-tryptophan as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed