BDBM50590755 CHEMBL5204912

SMILES FC(F)(F)c1cc(NC[C@H]2CCCN2)c2cn[nH]c2c1

InChI Key InChIKey=RCCAGXPMHDFDHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590755   

TargetTryptophan 2,3-dioxygenase(Human)
Xihua University

Curated by ChEMBL
LigandPNGBDBM50590755(CHEMBL5204912)
Affinity DataIC50: 6.09E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human TDO (19 to 388 residues) expressed in Escherichia coli Transetta (DE3) using L-tryptophan as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Xihua University

Curated by ChEMBL
LigandPNGBDBM50590755(CHEMBL5204912)
Affinity DataIC50: 9.58E+3nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human IDO1 (12 to 403 residues) expressed in Escherichia coli Transetta (DE3) using L-tryptophan as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed