BDBM50590855 CHEMBL5171791

SMILES CN1CCC(=O)NCCSCCS(=O)(=O)CCN(Cc2ccc(cc2)C#N)CC(=O)N[C@@H](Cc2cc3ccc(Cl)cc3[nH]2)C1=O

InChI Key InChIKey=NGYBSBQRYYOXPH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590855   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50590855(CHEMBL5171791)
Affinity DataIC50: 600nMAssay Description:Inhibition of MDM2 (unknown origin) by Fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50590855(CHEMBL5171791)
Affinity DataKd:  5.50E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed