BDBM50591308 CHEMBL5177166

SMILES NC(CCOc1ccc(cc1)S(N)(=O)=O)C1COc2ccccc2O1

InChI Key InChIKey=GHVPEVBTYVRTHA-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50591308   

TargetCarbonic anhydrase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant CA2 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant CA5B assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-AMC as substrate incubated for 30 mins by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  94nMAssay Description:Inhibition of human recombinant CA5A assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  133nMAssay Description:Inhibition of human recombinant CA9 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]-prazosin from human adrenergic alpha1A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  262nMAssay Description:Inhibition of human recombinant CA1 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591308(CHEMBL5177166)
Affinity DataKi:  3.03E+3nMAssay Description:Inhibition of human recombinant CA4 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed