BDBM50591309 CHEMBL5193531

SMILES COc1cc(ccc1OCCC(N)C1COc2ccccc2O1)S(N)(=O)=O

InChI Key InChIKey=KOIYEFLKONFTEX-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50591309   

TargetCarbonic anhydrase 9(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  31nMAssay Description:Inhibition of human recombinant CA9 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  410nMAssay Description:Inhibition of human recombinant CA5B assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  456nMAssay Description:Inhibition of human recombinant CA5A assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  478nMAssay Description:Inhibition of human recombinant CA4 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  843nMAssay Description:Inhibition of human recombinant CA2 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataKi:  914nMAssay Description:Inhibition of human recombinant CA1 assessed as inhibition constant pre-incubated for 15 mins measured by phenol red dye based stopped flow CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50591309(CHEMBL5193531)
Affinity DataIC50: 5.74E+4nMAssay Description:Inhibition of human recombinant DPP4 using H-Gly-Pro-AMC as substrate incubated for 30 mins by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed