BDBM50591648 CHEMBL5199795

SMILES C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(=O)NCC1CN(CC(=O)NO)N=N1)c3=O

InChI Key InChIKey=WRAVLPXLPCQONL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591648   

TargetHistone deacetylase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591648(CHEMBL5199795)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC1 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591648(CHEMBL5199795)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human HDAC2 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50591648(CHEMBL5199795)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human HDAC6 using HDAC substrate incubated for 30 mins by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed