BDBM50591738 CHEMBL5193862

SMILES c1ccc(c(c1)C(=O)NN2c3cc(c(cc3NC(=O)C2=O)C(F)(F)F)F)O

InChI Key InChIKey=MCKOVZZCGOMMIB-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50591738   

TargetGlutamate receptor ionotropic, kainate 3(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  142nMAssay Description:Binding affinity to GluK3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  908nMAssay Description:Binding affinity to GluK2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity to GluK1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor 2(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  4.12E+3nMAssay Description:Binding affinity to GluA2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Human)
Central South University

Curated by ChEMBL
LigandPNGBDBM50591738(CHEMBL5193862)
Affinity DataKi:  2.64E+4nMAssay Description:Binding affinity to GluK5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed