BDBM50592346 CHEMBL5190773

SMILES [H][C@@]12COP(S)(=O)O[C@@]3([H])[C@@H](O)[C@@H](O[C@]3([H])COP(S)(=O)O[C@]([H])([C@@H]1O)[C@@H](O2)n1cnc2c(N)ncnc12)n1cnc2c(N)ncnc12

InChI Key InChIKey=IZJJFUQKKZFVLH-UHFFFAOYSA-N

Data  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50592346   

TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  4.15E+4nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  2.92E+3nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 24 hrs by QUANTI-Luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  154nMAssay Description:Agonist activity at STING in human THP-1 reporter cells incubated for 4 hrs in presence of lipofectamine 2000 by QUANTI-Luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  131nMAssay Description:Agonist activity at STING in PMA-treated human THP-1 reporter cells incubated for 30 mins in presence of digitonin by QUANTI-Luc assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  4.15E+4nMAssay Description:Agonist activity at STING in human THP-1 cells by IFN-reporter based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  260nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  1.01E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  2.42E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  3.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed